AnVil provides a scientific perspective, focused on in silico drug discovery and drug development solutions. We partner with companies in the pharmaceutical, biotechnology, and other life sciences to extract knowledge from their data and enable them to turn it into commercially valuable results.

We can help you efficiently achieve the kinds of goals that usually take huge amounts of time and money. Here are some examples of where we can make an impact on your business goals:

• Decide which drugs to bring to market, cutting the time and costs involved along all stages of the pipeline
• Determine which molecules to bring to clinical trials
• Determine how to segment patients by disease sub-types
• Identify which patients will likely respond to treatment
• Decide which chemicals are likely to be toxic before synthesizing them

For details of how AnVil has provided valuable services to its clients, see the following case studies:

• Gene Expression for DNA Microarrays
  AnVil identified a set of genes that could accurately differentiate among normal and two cancer subtypes for a developer of high-throughput DNA-chip platform technology.
• Chemical Structure Activity Relationships
  AnVil enabled a combinatorial chemistry client to select the best set of structural features that would optimize biological activity of small molecules prior to engaging in the more costly process of synthesis and in vivo testing.
• Toxicogenomics of Drug Candidates
  AnVil helped a top-10 pharmaceutical company understand the dose-dependent mechanisms of toxicity and efficacy, enabling them to make informed decisions earlier in the drug development process.
• Analysis of Golub and Slonim Data
  AnVil uncovered a gene predictor set for prediction of the success or failure of chemotherapy treatment for leukemia patients. Read an overview of the case study. or read a detailed account of AnVil's data analysis.

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