Contact: Jennifer Wu
VP, Marketing and Business Development
(978) 934-8821, Ext. 128
E-mail: jwu@anvilinformatics.com

Contact: Michael McManus
President & COO
(978) 934-8821, Ext. 129
E-mail: mmcmanus@anvilinformatics.com

June 13, 2000

AnVil Informatics, Inc. Appoints Dr. Michael J. McManus as President and Chief Operating Officer

Lowell, MA — AnVil Informatics, Inc. has announced the appointment of Michael J. McManus, Ph.D., to President and Chief Operating Officer. Howard Berke will remain in the position of Chief Executive Officer and a Board Director.

AnVil's cofounder and CEO, Howard Berke commented: "Michael has over ten years of senior management experience with a commercial software and e-commerce company, and he has been involved in all aspects of CambridgeSoft's operations. He brings a comprehensive understanding of the software industry and organizational dynamics in the startup environment. Michael will help guide AnVil's product development and business direction and provide leadership in the upcoming growth of the company."

"Our challenge is to broadly apply AnVil's technical expertise to the emerging bioinformatics market. High growth companies need to build their management team in order to successfully accomplish ambitious commercialization goals," commented Dr. Frank Hurley, Chairman of AnVil. " Michael's breadth of experience in the informatics industry provides a solid foundation for AnVil's commercial growth. Michael can greatly expand our customer base and provide professional management to AnVil's day- to-day operations."

Prior to joining AnVil, Dr. McManus served in various capacities during his ten-year tenure with CambridgeSoft. His positions included Vice President of Marketing, Director of Research and Development and Director of Technical Support. Prior to CambridgeSoft, Dr. McManus was with Eastman Kodak Company, and US Government Army Material and Mechanics Research Center.

Dr. McManus received his Ph.D. from Massachusetts Institute of Technology (MIT) and a B.S. from University of Massachusetts, Amherst. Dr. McManus is also the holder of three U.S. patents.

Founded in 1999, AnVil Informatics, Inc. provides data mining and visualization services to leading pharmaceutical and biotechnology companies. AnVil's combination of unique, internally developed software and commercial tools allows for the exploration of complex, large and high dimensional datasets. In addition, AnVil's technical experts harness different properties of human perception such as color, texture and shape in the process of visualizing various attributes of the complex data and their full distributions. The resulting visualizations make conclusions more evident earlier in the decision making process and can greatly enhance every step of the client's decision making process--helping them to make informed decisions faster and more accurately.

To learn more about AnVil's capabilities and offerings, visit the web site at www.anvilinformatics.com.